Non-alcoholic fatty liver disease (NAFLD) is considered one of the most frequent liver diseases nowadays. It is mostly related to diabetes mellitus and obesity. Type 2 diabetes mellitus (DM2) is the risk factor that is more related to the progression and the gravity of NAFLD, increasing the risk of turning it into cirrhosis and cancer. Environmental factors, such as non-healthy eating habits, have got a crucial part in its pathophysiology. The present study aims to analyze the effect of nutritional therapy on NAFLD in diabetic patients. Methods: A review of the literature was made in the SciELO, PubMed and Lilacs database. Results/Discussion: As an effect of the nutritional therapy, it is expected the decrease of histologic features and an improvement in the insulin resistance and the level of liver enzymes. The supplementation with antioxidants, such as Vitamin E and Omega-3 fatty acids are quite inconsistent in the treatment of NAFLD. Conclusion: Nutritional therapy is fundamental in the treatment of NAFLD and must be modulated according to the presence or absence of obesity and the metabolic risk factors associated. It must be emphasized, still, that a balanced diet associated with the regular practice of physical activities is beneficial to the treatment. Nevertheless, more studies need to be done, since there’s no consent whether the management of a diet must be or must not be associated with supplementation and there's a lack of studies in the literature related to the therapy of NAFLD focused on diabetic patients.
