No clinical utility of KRAS variant rs61764370 for ovarian or breast cancer

Ovarian Cancer Association Consortium; Breast Cancer Association Consortium; Hollestelle, Antoinette; van der Baan, Frederieke H.; Berchuck, Andrew; Johnatty, Sharon E.; Aben, Katja K.; Agnarsson, Bjarni A.; Aittomäki, Kristiina; Alducci, Elisa; Andrulis, Irene L.; Anton-Culver, Hoda; Antonenkova, Natalia N.; Antoniou, Antonis C.; Apicella, Carmel; Arndt, Volker; Arnold, Norbert; Arun, Banu K.; Arver, Brita; Ashworth, Alan; Australian Ovarian Cancer Study Group; Baglietto, Laura; Balleine, Rosemary; Bandera, Elisa V.; Barrowdale, Daniel; Bean, Yukie T.; Beckmann, Lars; Beckmann, Matthias W.; Benitez, Javier; Berger, Andreas; Berger, Raanan; Beuselinck, Benoit; Bisogna, Maria; Bjorge, Line; Blomqvist, Carl; Bogdanova, Natalia V.; Bojesen, Anders; Bojesen, Stig E.; Bolla, Manjeet K.; Bonanni, Bernardo; Brand, Judith S.; Brauch, Hiltrud; Breast Cancer Family Register; Brenner, Hermann; Brinton, Louise; Brooks-Wilson, Angela; Bruinsma, Fiona; Brunet, Joan; Brüning, Thomas; Budzilowska, Agnieszka; Bunker, Clareann H.; Burwinkel, Barbara; Butzow, Ralf; Buys, Saundra S.; Caligo, Maria A.; Campbell, Ian; Carter, Jonathan; Chang-Claude, Jenny; Chanock, Stephen J.; M. Claes, Kathleen B.; Collée, J. Margriet; Cook, Linda S.; Couch, Fergus J.; Cox, Angela; Cramer, Daniel; Cross, Simon S.; Cunningham, Julie M.; Cybulski, Cezary; Czene, Kamila; Damiola, Francesca; Dansonka-Mieszkowska, Agnieszka; Darabi, Hatef; de la Hoya, Miguel; de Fazio, Anna; Dennis, Joseph; Devilee, Peter; Dicks, Ed M.; Diez, Orland; Doherty, Jennifer A.; Domchek, Susan M.; Dorfling, Cecilia M.; Dörk, Thilo; Dos Santos Silva, Isabel; du Bois, Andreas; Dumont, Martine; Dunning, Alison M.; Duran, Mercedes; Easton, Douglas F.; Eccles, Diana; Edwards, Robert P.; Ehrencrona, Hans; Ejlertsen, Bent; Ekici, Arif B.; Ellis, Steve D.; EMBRACE; Engel, Christoph; Eriksson, Mikael; Fasching, Peter A.; Feliubadalo, Lidia; Figueroa, Jonine; Flesch-Janys, Dieter; Fletcher, Olivia; Fontaine, Annette; Fortuzzi, Stefano; Fostira, Florentia; Fridley, Brooke L.; Friebel, Tara; Friedman, Eitan; Friel, Grace; Frost, Debra; Garbe, Judy; García-Closas, Montserrat; Gayther, Simon A.; GEMO Study Collaborators; GENICA Network; Gentry-Maharaj, Aleksandra; Anne-Marie, Gerdes; Giles, Graham G.; Glasspool, Rosalind; Glendon, Gord; Godwin, Andrew K.; Goodman, Marc T.; Gore, Martin; Greene, Mark H.; Grip, Mervi; Gronwald, Jacek; Gschwantler Kaulich, Daphne; Guénel, Pascal; Guzman, Starr R.; Haeberle, Lothar; Haiman, Christopher A.; Hall, Per; Halverson, Sandra L.; Hamann, Ute; O. Hansen, Thomas V.; Harter, Philipp; Hartikainen, Jaana M.; Healey, Sue; HEBON; Hein, Alexander; Heitz, Florian; Henderson, Brian E.; Herzog, Josef; T Hildebrandt, Michelle A.; Høgdall, Claus K.; Høgdall, Estrid; L. Hogervorst, Frans B.; Hopper, John L.; Humphreys, Keith; Huzarski, Tomasz; Imyanitov, Evgeny N.; Isaacs, Claudine; Jakubowska, Anna; Janavicius, Ramunas; Jaworska, Katarzyna; Jensen, Allan; Birk Jensen, Uffe; Johnson, Nichola; Jukkola-Vuorinen, Arja; Kabisch, Maria; Karlan, Beth Y.; Kataja, Vesa; Kauff, Noah; KConFab Investigators; Kelemen, Linda E.; Kerin, Michael J.; Kiemeney, Lambertus A.; Kjaer, Susanne K.; Knight, Julia A.; Knol-Bout, Jacoba P.; Konstantopoulou, Irene; Kosma, Veli-Matti; Krakstad, Camilla; Kristensen, Vessela; Kuchenbaecker, Karoline B.; Kupryjanczyk, Jolanta; Laitman, Yael; Lambrechts, Diether; Lambrechts, Sandrina; Larson, Melissa C.; Lasa, Adriana; Laurent-Puig, Pierre; Lazaro, Conxi; Le, Nhu D.; Le Marchand, Loic; Leminen, Arto; Lester, Jenny; Levine, Douglas A.; Li, Jingmei; Liang, Dong; Lindblom, Annika; Lindor, Noralane; Lissowska, Jolanta; Long, Jirong; Lu, Karen H.; Lubinski, Jan; Lundvall, Lene; Lurie, Galina; Mai, Phuong L.; Mannermaa, Arto; Margolin, Sara; Mariette, Frederique; Marme, Frederik; M. Martens, John W.; G. Massuger, Leon F.A.; Maugard, Christine; Mazoyer, Sylvie; McGuffog, Lesley; McGuire, Valerie; McLean, Catriona; McNeish, Iain; Meindl, Alfons; Menegaux, Florence; Menéndez, Primitiva; Menkiszak, Janusz; Menon, Usha; Mensenkamp, Arjen R.; Miller, Nicola; Milne, Roger L.; Modugno, Francesmary; Montagna, Marco; Moysich, Kirsten B.; Müller, Heiko; Mulligan, Anna Marie; Muranen, Taru A.; Narod, Steven A.; Nathanson, Katherine L.; Ness, Roberta B.; Neuhausen, Susan L.; Nevanlinna, Heli; Neven, Patrick; Nielsen, Finn C.; Nielsen, Sune F.; Nordestgaard, Børge G.; Nussbaum, Robert L.; Odunsi, Kunle; Offit, Kenneth; Olah, Edith; Olopade, Olufunmilayo I.; Olson, Janet E.; Olson, Sara H.; Oosterwijk, Jan C.; Orlow, Irene; Orr, Nick; Orsulic, Sandra; Osorio, Ana; Ottini, Laura; Paul, James; Pearce, Celeste L.; Sokilde Pedersen, Inge; Peissel, Bernard; Pejovic, Tanja; Pelttari, Liisa M.; Perkins, Jo; Permuth-Wey, Jenny; Peterlongo, Paolo; Peto, Julian; Phelan, Catherine M.; Phillips, Kelly-Anne; Piedmonte, Marion; Pike, Malcolm C.; Platte, Radka; Plisiecka-Halasa, Joanna; Poole, Elizabeth M.; Poppe, Bruce; Pylkäs, Katri; Radice, Paolo; Ramus, Susan J.; Rebbeck, Timothy R.; R. Reed, Malcolm W.; Rennert, Gad; Risch, Harvey A.; Robson, Mark; Rodriguez, Gustavo C.; Romero, Atocha; Rossing, Mary Anne; Rothstein, Joseph H.; Rudolph, Anja; Runnebaum, Ingo; Salani, Ritu; Salvesen, Helga B.; Sawyer, Elinor J.; Schildkraut, Joellen M.; Schmidt, Marjanka K.; Schmutzler, Rita K.; Schneeweiss, Andreas; Schoemaker, Minouk J.; Schrauder, Michael G.; Schumacher, Fredrick; Schwaab, Ira; Scuvera, Giulietta; Sellers, Thomas A.; Severi, Gianluca; Seynaeve, Caroline M.; Shah, Mitul; Shrubsole, Martha; Siddiqui, Nadeem; Sieh, Weiva; Simard, Jacques; Singer, Christian F.; Sinilnikova, Olga M.; Smeets, Dominiek; Sohn, Christof; Soller, Maria; Song, Honglin; Soucy, Penny; Southey, Melissa C.; Stegmaier, Christa; Stoppa-Lyonnet, Dominique; Sucheston, Lara; SWE-BRCA; Swerdlow, Anthony; Tangen, Ingvild L.; Tea, Muy-Kheng; Teixeira, Manuel R.; Terry, Kathryn L.; Terry, Mary Beth; Thomassen, Mads; Thompson, Pamela J.; Tihomirova, Laima; Tischkowitz, Marc; Ewart Toland, Amanda; M. Tollenaar, Rob A.E.; Tomlinson, Ian; Torres, Diana; Truong, Thérèse; Tsimiklis, Helen; Tung, Nadine; Tworoger, Shelley S.; Tyrer, Jonathan P.; Vachon, Celine M.; Van 't Veer, Laura J.; van Altena, Anne M.; Van Asperen, C.J.; van den Berg, David; van den Ouweland, Ans M.W.; van Doorn, Helena C.; Van Nieuwenhuysen, Els; van Rensburg, Elizabeth J.; Vergote, Ignace; Verhoef, Senno; Vierkant, Robert A.; Vijai, Joseph; Vitonis, Allison F.; von Wachenfeldt, Anna; Walsh, Christine; Wang, Qin; Wang-Gohrke, Shan; Wappenschmidt, Barbara; Weischer, Maren; Weitzel, Jeffrey N.; Weltens, Caroline; Wentzensen, Nicolas; Whittemore, Alice S.; Wilkens, Lynne R.; Winqvist, Robert; Wu, Anna H.; Wu, Xifeng; Yang, Hannah P.; Zaffaroni, Daniela; Zamora, M. Pilar; Zheng, Wei; Ziogas, Argyrios; Chenevix-Trench, Georgia; P. Pharoah, Paul D.; Rookus, Matti A.; Hooning, Maartje J.; Goode, Ellen L.

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iCOGS_KRASPLOSMedicine.pdf (1.188Mb)

Autor

Ovarian Cancer Association Consortium

Breast Cancer Association Consortium

Hollestelle, Antoinette

van der Baan, Frederieke H.

Berchuck, Andrew

Johnatty, Sharon E.

Aben, Katja K.

Agnarsson, Bjarni A.

Aittomäki, Kristiina

Alducci, Elisa

Andrulis, Irene L.

Anton-Culver, Hoda

Antonenkova, Natalia N.

Antoniou, Antonis C.

Apicella, Carmel

Arndt, Volker

Arnold, Norbert

Arun, Banu K.

Arver, Brita

Ashworth, Alan

Australian Ovarian Cancer Study Group

Baglietto, Laura

Balleine, Rosemary

Bandera, Elisa V.

Barrowdale, Daniel

Bean, Yukie T.

Beckmann, Lars

Beckmann, Matthias W.

Benitez, Javier

Berger, Andreas

Berger, Raanan

Beuselinck, Benoit

Bisogna, Maria

Bjorge, Line

Blomqvist, Carl

Bogdanova, Natalia V.

Bojesen, Anders

Bojesen, Stig E.

Bolla, Manjeet K.

Bonanni, Bernardo

Brand, Judith S.

Brauch, Hiltrud

Breast Cancer Family Register

Brenner, Hermann

Brinton, Louise

Brooks-Wilson, Angela

Bruinsma, Fiona

Brunet, Joan

Brüning, Thomas

Budzilowska, Agnieszka

Bunker, Clareann H.

Burwinkel, Barbara

Butzow, Ralf

Buys, Saundra S.

Caligo, Maria A.

Campbell, Ian

Carter, Jonathan

Chang-Claude, Jenny

Chanock, Stephen J.

M. Claes, Kathleen B.

Collée, J. Margriet

Cook, Linda S.

Couch, Fergus J.

Cox, Angela

Cramer, Daniel

Cross, Simon S.

Cunningham, Julie M.

Cybulski, Cezary

Czene, Kamila

Damiola, Francesca

Dansonka-Mieszkowska, Agnieszka

Darabi, Hatef

de la Hoya, Miguel

de Fazio, Anna

Dennis, Joseph

Devilee, Peter

Dicks, Ed M.

Diez, Orland

Doherty, Jennifer A.

Domchek, Susan M.

Dorfling, Cecilia M.

Dörk, Thilo

Dos Santos Silva, Isabel

du Bois, Andreas

Dumont, Martine

Dunning, Alison M.

Duran, Mercedes

Easton, Douglas F.

Eccles, Diana

Edwards, Robert P.

Ehrencrona, Hans

Ejlertsen, Bent

Ekici, Arif B.

Ellis, Steve D.

EMBRACE

Engel, Christoph

Eriksson, Mikael

Fasching, Peter A.

Feliubadalo, Lidia

Figueroa, Jonine

Flesch-Janys, Dieter

Fletcher, Olivia

Fontaine, Annette

Fortuzzi, Stefano

Fostira, Florentia

Fridley, Brooke L.

Friebel, Tara

Friedman, Eitan

Friel, Grace

Frost, Debra

Garbe, Judy

García-Closas, Montserrat

Gayther, Simon A.

GEMO Study Collaborators

GENICA Network

Gentry-Maharaj, Aleksandra

Anne-Marie, Gerdes

Giles, Graham G.

Glasspool, Rosalind

Glendon, Gord

Godwin, Andrew K.

Goodman, Marc T.

Gore, Martin

Greene, Mark H.

Grip, Mervi

Gronwald, Jacek

Gschwantler Kaulich, Daphne

Guénel, Pascal

Guzman, Starr R.

Haeberle, Lothar

Haiman, Christopher A.

Hall, Per

Halverson, Sandra L.

Hamann, Ute

O. Hansen, Thomas V.

Harter, Philipp

Hartikainen, Jaana M.

Healey, Sue

HEBON

Hein, Alexander

Heitz, Florian

Henderson, Brian E.

Herzog, Josef

T Hildebrandt, Michelle A.

Høgdall, Claus K.

Høgdall, Estrid

L. Hogervorst, Frans B.

Hopper, John L.

Humphreys, Keith

Huzarski, Tomasz

Imyanitov, Evgeny N.

Isaacs, Claudine

Jakubowska, Anna

Janavicius, Ramunas

Jaworska, Katarzyna

Jensen, Allan

Birk Jensen, Uffe

Johnson, Nichola

Jukkola-Vuorinen, Arja

Kabisch, Maria

Karlan, Beth Y.

Kataja, Vesa

Kauff, Noah

KConFab Investigators

Kelemen, Linda E.

Kerin, Michael J.

Kiemeney, Lambertus A.

Kjaer, Susanne K.

Knight, Julia A.

Knol-Bout, Jacoba P.

Konstantopoulou, Irene

Kosma, Veli-Matti

Krakstad, Camilla

Kristensen, Vessela

Kuchenbaecker, Karoline B.

Kupryjanczyk, Jolanta

Laitman, Yael

Lambrechts, Diether

Lambrechts, Sandrina

Larson, Melissa C.

Lasa, Adriana

Laurent-Puig, Pierre

Lazaro, Conxi

Le, Nhu D.

Le Marchand, Loic

Leminen, Arto

Lester, Jenny

Levine, Douglas A.

Li, Jingmei

Liang, Dong

Lindblom, Annika

Lindor, Noralane

Lissowska, Jolanta

Long, Jirong

Lu, Karen H.

Lubinski, Jan

Lundvall, Lene

Lurie, Galina

Mai, Phuong L.

Mannermaa, Arto

Margolin, Sara

Mariette, Frederique

Marme, Frederik

M. Martens, John W.

G. Massuger, Leon F.A.

Maugard, Christine

Mazoyer, Sylvie

McGuffog, Lesley

McGuire, Valerie

McLean, Catriona

McNeish, Iain

Meindl, Alfons

Menegaux, Florence

Menéndez, Primitiva

Menkiszak, Janusz

Menon, Usha

Mensenkamp, Arjen R.

Miller, Nicola

Milne, Roger L.

Modugno, Francesmary

Montagna, Marco

Moysich, Kirsten B.

Müller, Heiko

Mulligan, Anna Marie

Muranen, Taru A.

Narod, Steven A.

Nathanson, Katherine L.

Ness, Roberta B.

Neuhausen, Susan L.

Nevanlinna, Heli

Neven, Patrick

Nielsen, Finn C.

Nielsen, Sune F.

Nordestgaard, Børge G.

Nussbaum, Robert L.

Odunsi, Kunle

Offit, Kenneth

Olah, Edith

Olopade, Olufunmilayo I.

Olson, Janet E.

Olson, Sara H.

Oosterwijk, Jan C.

Orlow, Irene

Orr, Nick

Orsulic, Sandra

Osorio, Ana

Ottini, Laura

Paul, James

Pearce, Celeste L.

Sokilde Pedersen, Inge

Peissel, Bernard

Pejovic, Tanja

Pelttari, Liisa M.

Perkins, Jo

Permuth-Wey, Jenny

Peterlongo, Paolo

Peto, Julian

Phelan, Catherine M.

Phillips, Kelly-Anne

Piedmonte, Marion

Pike, Malcolm C.

Platte, Radka

Plisiecka-Halasa, Joanna

Poole, Elizabeth M.

Poppe, Bruce

Pylkäs, Katri

Radice, Paolo

Ramus, Susan J.

Rebbeck, Timothy R.

R. Reed, Malcolm W.

Rennert, Gad

Risch, Harvey A.

Robson, Mark

Rodriguez, Gustavo C.

Romero, Atocha

Rossing, Mary Anne

Rothstein, Joseph H.

Rudolph, Anja

Runnebaum, Ingo

Salani, Ritu

Salvesen, Helga B.

Sawyer, Elinor J.

Schildkraut, Joellen M.

Schmidt, Marjanka K.

Schmutzler, Rita K.

Schneeweiss, Andreas

Schoemaker, Minouk J.

Schrauder, Michael G.

Schumacher, Fredrick

Schwaab, Ira

Scuvera, Giulietta

Sellers, Thomas A.

Severi, Gianluca

Seynaeve, Caroline M.

Shah, Mitul

Shrubsole, Martha

Siddiqui, Nadeem

Sieh, Weiva

Simard, Jacques

Singer, Christian F.

Sinilnikova, Olga M.

Smeets, Dominiek

Sohn, Christof

Soller, Maria

Song, Honglin

Soucy, Penny

Southey, Melissa C.

Stegmaier, Christa

Stoppa-Lyonnet, Dominique

Sucheston, Lara

SWE-BRCA

Swerdlow, Anthony

Tangen, Ingvild L.

Tea, Muy-Kheng

Teixeira, Manuel R.

Terry, Kathryn L.

Terry, Mary Beth

Thomassen, Mads

Thompson, Pamela J.

Tihomirova, Laima

Tischkowitz, Marc

Ewart Toland, Amanda

M. Tollenaar, Rob A.E.

Tomlinson, Ian

Torres, Diana

Truong, Thérèse

Tsimiklis, Helen

Tung, Nadine

Tworoger, Shelley S.

Tyrer, Jonathan P.

Vachon, Celine M.

Van 't Veer, Laura J.

van Altena, Anne M.

Van Asperen, C.J.

van den Berg, David

van den Ouweland, Ans M.W.

van Doorn, Helena C.

Van Nieuwenhuysen, Els

van Rensburg, Elizabeth J.

Vergote, Ignace

Verhoef, Senno

Vierkant, Robert A.

Vijai, Joseph

Vitonis, Allison F.

von Wachenfeldt, Anna

Walsh, Christine

Wang, Qin

Wang-Gohrke, Shan

Wappenschmidt, Barbara

Weischer, Maren

Weitzel, Jeffrey N.

Weltens, Caroline

Wentzensen, Nicolas

Whittemore, Alice S.

Wilkens, Lynne R.

Winqvist, Robert

Wu, Anna H.

Wu, Xifeng

Yang, Hannah P.

Zaffaroni, Daniela

Zamora, M. Pilar

Zheng, Wei

Ziogas, Argyrios

Chenevix-Trench, Georgia

P. Pharoah, Paul D.

Rookus, Matti A.

Hooning, Maartje J.

Goode, Ellen L.

Excepto si se señala otra cosa, la licencia del ítem se describe como http://creativecommons.org/licenses/by-nc/4.0/