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dc.creatorSchnakers, Caroline
dc.creatorBauer, Chase
dc.creatorFormisano, Rita
dc.creatorNoé, Enrique
dc.creatorLlorens, Roberto
dc.creatorLejeune, Nicolas
dc.creatorFarisco, Michele
dc.creatorTeixeira, Liliana
dc.creatorMorrissey, Ann-Marie
dc.creatorDe Marco, Sabrina
dc.creatorVeeramuthu, Vigneswaran
dc.creatorIlina, Kseniya
dc.creatorEdlow, Brian L.
dc.creatorGosseries, Olivia
dc.creatorZandalasini, Matteo
dc.creatorDe Bellis, Francesco
dc.creatorThibaut, Aurore
dc.creatorEstraneo, Anna
dc.date2022-08-05
dc.date.accessioned2022-09-21T22:03:38Z
dc.date.available2022-09-21T22:03:38Z
dc.identifierhttp://pa.bibdigital.ucc.edu.ar/3336/1/Schnakers_Bauer_Formisano.pdf
dc.identifier.urihttps://hdl.handle.net/20.500.12032/46190
dc.descriptionBackground: With the emergence of Brain Computer Interfaces (BCI), clinicians have been facing a new group of patients with severe acquired brain injury who are unable to show any behavioral sign of consciousness but respond to active neuroimaging or electrophysiological paradigms. However, even though well documented, there is still no consensus regarding the nomenclature for this clinical entity. Objectives: This systematic review aims to 1) identify the terms used to indicate the presence of this entity through the years, and 2) promote an informed discussion regarding the rationale for these names and the best candidates to name this fascinating disorder. Methods: The Disorders of Consciousness Special Interest Group (DoC SIG) of the International Brain Injury Association (IBIA) launched a search on Pubmed and Google scholar following PRISMA guidelines to collect peer-reviewed articles and reviews on human adults (>18 years) published in English between 2006 and 2021. Results: The search launched in January 2021 identified 4,089 potentially relevant titles. After screening, 1,126 abstracts were found relevant. Finally, 161 manuscripts were included in our analyses. Only 58% of the manuscripts used a specific name to discuss this clinical entity, among which 32% used several names interchangeably throughout the text. We found 25 different names given to this entity. The five following names were the ones the most frequently used: covert awareness, cognitive motor dissociation, functional locked-in, non-behavioral MCS (MCS*) and higher-order cortex motor dissociation. Conclusion: Since 2006, there has been no agreement regarding the taxonomy to use for unresponsive patients who are able to respond to active neuroimaging or electrophysiological paradigms. Developing a standard taxonomy is an important goal for future research studies and clinical translation. We recommend a Delphi study in order to build such a consensus.
dc.descriptionFil: Schnakers, Caroline. Casa Colina Hospital and Centers for Healthcare. Research Institute; Estados Unidos
dc.descriptionFil: Bauer, Chase. Western University of Health Sciences. College of Osteopathic Medicine; Estados Unidos
dc.descriptionFil: Formisano, Rita. IRCCS Santa Lucia Foundation; Italia
dc.descriptionFil: Noé, Enrique. Fundación Hospitales Vithas. Vithas Neuro Rehab Human Brain; España
dc.descriptionFil: Llorens, Roberto. Fundación Hospitales Vithas. Vithas Neuro Rehab Human Brain; España
dc.descriptionFil: Llorens, Roberto. Universitat Politècnica de València. Instituto de Investigación e Innovación en Bioingeniería. Neurorehabilitation and Brain Research Group; España
dc.descriptionFil: Lejeune, Nicolas. University of Liège. Coma Science Group. GIGA-Consciousness; Bélgica
dc.descriptionFil: Lejeune, Nicolas. Ottignies-Louvain-la-Neuve. Centre Hospitalier Neurologique William Lennox; Bélgica
dc.descriptionFil: Farisco, Michele. Uppsala University. Centre for Research Ethics and Bioethics,; Suecia
dc.descriptionFil: Farisco, Michele. Biology and Molecular Genetics Research Institute. Science and Society Unit, Biogem; Italia
dc.descriptionFil: Teixeira, Liliana. Polytechnic of Leiria. School of Health Sciences. Center for Innovative Care and Health Technology; Portugal
dc.descriptionFil: Morrissey, Ann-Marie. University of Limerick. Health Research Institute. Ageing Research Centre; Irlanda
dc.descriptionFil: De Marco, Sabrina. Universidad Católica de Córdoba. Clínica Universitaria Reina Fabiola; Argentina
dc.descriptionFil: Veeramuthu, Vigneswaran. Subang Jaya Medical Center; Malasia
dc.descriptionFil: Ilina, Kseniya. Research Center of Neurology; Rusia
dc.descriptionFil: Ilina, Kseniya. Lomonosov Moscow State University. Faculty of Fundamental Medicine; Rusia
dc.descriptionFil: Edlow, Brian L. Harvard Medical School. Massachusetts General Hospital; Estados Unidos
dc.descriptionFil: Gosseries, Olivia. University of Liège. Coma Science Group; Bélgica
dc.descriptionFil: Gosseries, Olivia. University Hospital of Liege. Centre du Cerveau; Bélgica
dc.descriptionFil: Zandalasini, Matteo. Azienda USL di Piacenza. Dipartimento di Medicina Riabilitativa. Neuroriabilitazione e Medicina Riabilitativa Intensiva. Unità Spinale; Italia
dc.descriptionFil: De Bellis, Francesco. IRCCS Fondazione Don Carlo Gnocchi; Italia
dc.descriptionFil: Thibaut, Aurore. University of Liège. Coma Science Group. GIGA-Consciousness; Bélgica
dc.descriptionFil: Thibaut, Aurore. University Hospital of Liege. Centre du Cerveau; Bélgica
dc.descriptionFil: Estraneo, Anna. IRCCS Fondazione Don Carlo Gnocchi; Italia
dc.descriptionFil: Estraneo, Anna. SM della Pietà General Hospital. Neurology Unit; Italia
dc.formatapplication/pdf
dc.languagespa
dc.publisherFrontiers Media S.A.
dc.relationhttp://pa.bibdigital.ucc.edu.ar/3336/
dc.relationhttps://www.frontiersin.org/articles/10.3389/fnhum.2022.971315/full
dc.relationinfo:eu-repo/semantics/altIdentifier/doi/https://doi.org/10.3389/fnhum.2022.971315
dc.rightsinfo:eu-repo/semantics/openAccess
dc.rightshttps://creativecommons.org/licenses/by-nc-nd/4.0/deed.es
dc.sourceSchnakers, Caroline, Bauer, Chase, Formisano, Rita ORCID: https://orcid.org/0000-0002-2516-0540 <https://orcid.org/0000-0002-2516-0540>, Noé, Enrique ORCID: https://orcid.org/0000-0002-2547-8727 <https://orcid.org/0000-0002-2547-8727>, Llorens, Roberto ORCID: https://orcid.org/0000-0002-8677-8707 <https://orcid.org/0000-0002-8677-8707>, Lejeune, Nicolas, Farisco, Michele, Teixeira, Liliana, Morrissey, Ann-Marie, De Marco, Sabrina, Veeramuthu, Vigneswaran, Ilina, Kseniya, Edlow, Brian L., Gosseries, Olivia, Zandalasini, Matteo, De Bellis, Francesco, Thibaut, Aurore ORCID: https://orcid.org/0000-0001-5991-1747 <https://orcid.org/0000-0001-5991-1747> and Estraneo, Anna (2022) What names for covert awareness? A systematic review. Frontiers in Human Neuroscience, 16. ISSN 1662-5161
dc.subjectR Medicina (General)
dc.subjectRC0321 Neurociencia. La psiquiatría biológica. Neuropsiquiatría
dc.titleWhat names for covert awareness? A systematic review
dc.typeinfo:eu-repo/semantics/article
dc.typeinfo:ar-repo/semantics/artículo


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